This peer-reviewed study examined the probiotic effects of Bacillus clausii in male Albino Sprague-Dawley rats infected with E. coli. Treatment with B. clausii significantly improved total protein, albumin levels, and other biochemical parameters (P < 0.05), reducing the negative impacts of infection. The findings highlight its therapeutic potential against antibiotic-resistant E. coli, recommending further research.

This peer-reviewed analysis assessed the quality of B. clausii probiotic products like Enterogermina and Bifilac clausii, focusing on purity, viable spore load, and antibiotic resistance. Products showed resistance to chloramphenicol, streptomycin, tetracycline, and rifampicin, confirming their functionality during antibiotic therapy. It is the first comprehensive evaluation using pharmacopoeia methods, though limited by lack of molecular strain identification.

This peer-reviewed study investigated the gastrointestinal tract resistance and safety of potential probiotic Bacillus species, including B. clausii. It evaluated their ability to withstand GI conditions like acidic pH and bile salts. The research emphasizes safety profiles for probiotic applications.