A systematic review and meta-analysis of three studies with 248 participants found that a one-gram daily dose of olive leaf extract reduced systolic blood pressure by 11.45 mmHg and diastolic by 4.65 mmHg in hypertensive or pre-hypertensive adults. Researchers from Instituto Politécnico de Bragança highlight its potential as a herbal treatment for hypertension, supported by bioactive compounds like oleuropein. Published in Phytotherapy Research.

A randomized, double-blind, placebo-controlled study with 65 postmenopausal women showed 12 weeks of 250 mg daily olive leaf extract stabilized elastin levels and reduced pentosidine (an advanced glycation end-product), with trends toward better skin quality including reduced pore number and surface skewness. While not all results were significant after correction, findings suggest potential benefits for tissue aging and skin structure in menopause. Exploratory analyses indicate localized dermal effects.

Multiple reviews and analyses of experimental studies show olive leaf extract improves heart disease risk factors, including blood pressure, lipids, and glucose control, with stronger effects in those with hypertension or high lipids. Doses ranged from 250-5000 mg daily over 6-48 weeks, though results vary due to differences in form, dose, and duration. More research is needed for consistency, but benefits align with olive polyphenols like oleuropein and hydroxytyrosol.